Department of Biotechnology
All India Institute of Medical Sciences (AIIMS)
New Delhi -110029, India
Translational Immunology, Osteoimmunology & Immunoporosis Lab
(TIOIL)
The birth place of "Immunoporosis" : Immunology of Osteoporosis
Publications:
2024
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Sapra L, Saini C, Sharma S, Nanda D, Nilakhe A, Chattopadhyay N, Meena AS, Mishra PK, Gupta S, Garg B, Manhas V, Srivastava RK. Targeting the osteoclastogenic cytokine IL-9 as a novel immunotherapeutic strategy in mitigating inflammatory bone loss in post-menopausal osteoporosis. JBMR Plus. 2024 Sep 14;8(11):ziae120. doi: 10.1093/jbmrpl/ziae120. PMID: 39399159; PMCID: PMC11470976.
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​Kapoor S, Gupta M, Sapra L, Kaur T and Srivastava RK* (2024). Targeting the osteoclastogenic cytokine IL-9 as a novel immunotherapeutic strategy in mitigating inflammatory bone loss in post-menopausal osteoporosis. Bone Reports (2024) 10 October. https://doi.org/10.1016/j.bonr.2024.101809
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Gupta K, Soni N, Nema RK, Sahu N, Srivastava RK, Ratre P, Mishra PK. Microcystin-LR in drinking water: An emerging role of mitochondrial-induced epigenetic modifications and possible mitigation strategies. Toxicol Rep. 2024 Sep 28;13:101745. doi: 10.1016/j.toxrep.2024.101745. PMID: 39411183; PMCID: PMC11474209.
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Yadav S, Sapra L, Srivastava RK. Polysaccharides to postbiotics: Nurturing bone health via modulating "gut-immune axis". Int J Biol Macromol. 2024 Oct;278(Pt 2):134655. doi: 10.1016/j.ijbiomac.2024.134655. Epub 2024 Aug 14. PMID: 39128750.
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Saini C, Sapra L, Puri P, Mishra PK, Chawla R, Srivastava RK. Dysregulated Th17/Treg cell axis is correlated with local and systemic immune response in human intermediate uveitis. Immunol Lett. 2024 Aug; 268:106888. doi: 10.1016/j.imlet.2024.106888. Epub 2024 Jun 24. PMID: 38925441.
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Sapra L, Saini C, Das S, Mishra PK, Singh A, Mridha AR, Yadav PK, Srivastava RK. Lactobacillus rhamnosus (LR) ameliorates pulmonary and extrapulmonary acute respiratory distress syndrome (ARDS) via targeting neutrophils. Clin Immunol. 2024 Jan;258:109872. doi: 10.1016/j.clim.2023.109872. Epub 2023 Dec 17. PMID: 38113963.
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​Pol V, Kaur T, Bhardwaj A, Sapra L, Yadav S and Srivastava RK*. Targeting “Immunoporosis” as a Novel Concept of Immunotherapy in the Management and Treatment of Osteoporosis. IntechOpen (2024). DOI: http://dx.doi.org/10.5772/intechopen.1003712
2023
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Srivastava RK, Sapra L, Bhardwaj A, Mishra PK, Verma B, Baig Z. Unravelling the immunobiology of innate lymphoid cells (ILCs): Implications in health and disease. Cytokine Growth Factor Rev. 2023 Dec;74:56-75. doi: 10.1016/j.cytogfr.2023.09.002. Epub 2023 Sep 16. PMID: 37743134.
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Anwar A, Sapra L, Gupta N, Ojha RP, Verma B, Srivastava RK. Fine-tuning osteoclastogenesis: An insight into the cellular and molecular regulation of osteoclastogenesis. J Cell Physiol. 2023 Jul;238(7):1431-1464. doi: 10.1002/jcp.31036. Epub 2023 May 14. PMID: 37183350.
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Srivastava RK, Duggal NA, Parameswaran N. Editorial: Gut microbiota and gut-associated metabolites in bone health. Front Endocrinol (Lausanne). 2023 Jul 20;14:1232050. doi: 10.3389/fendo.2023.1232050. PMID: 37547322; PMCID: PMC10400440.
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Saugandhika S, Sapra L, Kumari K, Srivastava RK. High Salt Diet Impairs Male Fertility in Mice via Modulating the Skeletal Homeostasis. Reprod Sci. 2023 Nov;30(11):3339-3352. doi: 10.1007/s43032-023-01278-w. Epub 2023 Jun 15. PMID: 37322320.
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Madhry D, Malvankar S, Phadnis S, Srivastava RK, Bhattacharyya S, Verma B. Synergistic correlation between host angiogenin and dengue virus replication. RNA Biol. 2023 Jan;20(1):805-816. doi: 10.1080/15476286.2023.2264003. Epub 2023 Oct 5. PMID: 37796112; PMCID: PMC10557563.
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Malvankar S, Singh A, Ravi Kumar YS, Sahu S, Shah M, Murghai Y, Seervi M, Srivastava RK, Verma B. Modulation of various host cellular machinery during COVID-19 infection. Rev Med Virol. 2023 Nov;33(6):e2481. doi: 10.1002/rmv.2481. Epub 2023 Sep 27. PMID: 37758688.
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Singh A, Pandey KK, Agrawal SK, Srivastava RK, Bhattacharyya S, Verma B. The SARS-CoV-2 UTR's Intrudes Host RBP's and Modulates Cellular Splicing. Adv Virol. 2023 Apr 5;2023: 2995443. doi: 10.1155/2023/2995443. PMID: 37065904; PMCID: PMC10098413.
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​Das S, Sharma T, Bhardwaj A, Srivastava RK*. COVID-19 induced ARDS: immunopathology and therapeutics. Explor Immunol. 2023;3:255–75. https://doi.org/10.37349/ei.2023.00101
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Azam Z, Sapra L, Baghel K, Sinha N, Gupta RK, Soni V, Saini C, Mishra PK, Srivastava RK. Cissus quadrangularis (Hadjod) Inhibits RANKL-Induced Osteoclastogenesis and Augments Bone Health in an Estrogen-Deficient Preclinical Model of Osteoporosis Via Modulating the Host Osteoimmune System. Cells. 2023 Jan 4;12(2):216. doi: 10.3390/cells12020216. PMID: 36672152; PMCID: PMC9857034.
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Ratre P, Nazeer N, Kumari R, Thareja S, Jain B, Tiwari R, Kamthan A, Srivastava RK, Mishra PK. Carbon-Based Fluorescent Nano-Biosensors for the Detection of Cell-Free Circulating MicroRNAs. Biosensors (Basel). 2023 Feb 4;13(2):226. doi: 10.3390/bios13020226. PMID: 36831992; PMCID: PMC9953975.
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Rehman A, Kumari R, Kamthan A, Tiwari R, Srivastava RK, van der Westhuizen FH, Mishra PK. Cell-free circulating mitochondrial DNA: An emerging biomarker for airborne particulate matter associated with cardiovascular diseases. Free Radic Biol Med. 2023 Feb 1;195:103-120. doi: 10.1016/j.freeradbiomed.2022.12.083. Epub 2022 Dec 28. PMID: 36584454.
2022
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Srivastava RK, Sapra L, Mishra PK. Osteometabolism: Metabolic Alterations in Bone Pathologies. Cells. 2022 Dec 6;11(23):3943. doi: 10.3390/cells11233943. PMID: 36497201; PMCID: PMC9735555.
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Dave JR, Chandekar SS, Behera S, Desai KU, Salve PM, Sapkal NB, Mhaske ST, Dewle AM, Pokare PS, Page M, Jog A, Chivte PA, Srivastava RK, Tomar GB. Human gingival mesenchymal stem cells retain their growth and immunomodulatory characteristics independent of donor age. Sci Adv. 2022 Jun 24;8(25):eabm6504. doi: 10.1126/sciadv.abm6504. Epub 2022 Jun 24. PMID: 35749495; PMCID: PMC9232118.
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Azam Z, Sapra L, Bhardwaj A, Yadav S, Mishra PK, Shukla P, Sharma V and Srivastava RK*. Crocin attenuates osteoclastogenesis and enhances bone health by skewing the immunoporotic “Treg-Th17” cell axis in post-menopausal osteoporotic mice model. Phytomedicine Plus (2022) 2 (3): 100302, 10.1016/j.phyplu.2022.100302 (IF: 6.6).
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Sapra L, Shokeen N, Porwal K, Saini C, Bhardwaj A, Mathew M, Mishra PK, Chattopadhyay N, Dar HY, Verma B, Srivastava RK. Bifidobacterium longum Ameliorates Ovariectomy-Induced Bone Loss via Enhancing Anti-Osteoclastogenic and Immunomodulatory Potential of Regulatory B Cells (Bregs). Front Immunol. 2022 May 25;13:875788. doi: 10.3389/fimmu.2022.875788. PMID: 35693779; PMCID: PMC9174515.
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Saini C, Sapra L, Bhardwaj A, Tarique M, Sharma A, Khanna N, Ramesh V, Puri P, Srivastava RK. IL-21 plays an important role in modulating "Th17-Treg" cell axis in leprosy Type 1 reactions. Cytokine. 2022 Apr;152:155821. doi: 10.1016/j.cyto.2022.155821. Epub 2022 Feb 10. PMID: 35151928.
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Sapra L, Saini C, Garg B, Gupta R, Verma B, Mishra PK, Srivastava RK. Long-term implications of COVID-19 on bone health: pathophysiology and therapeutics. Inflamm Res. 2022 Sep;71(9):1025-1040. doi: 10.1007/s00011-022-01616-9. Epub 2022 Jul 28. PMID: 35900380; PMCID: PMC9330992.
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Srivastava RK, Sapra L. The Rising Era of "Immunoporosis": Role of Immune System in the Pathophysiology of Osteoporosis. J Inflamm Res. 2022 Mar 5;15:1667-1698. doi: 10.2147/JIR.S351918. PMID: 35282271; PMCID: PMC8906861.
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Bhardwaj A, Sapra L, Tiwari A, Mishra PK, Sharma S, Srivastava RK. "Osteomicrobiology": The Nexus Between Bone and Bugs. Front Microbiol. 2022 Jan 25;12:812466. doi: 10.3389/fmicb.2021.812466. PMID: 35145499; PMCID: PMC8822158.
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Tiwari A, Kumar S, Choudhir G, Singh G, Gangwar U, Sharma V, Srivastava RK, Sharma S. Bioactive metabolites of edible mushrooms efficacious against androgenic alopecia: Targeting SRD5A2 using computational approach. Journal of Herbal Medicine (2022). doi: https://doi.org/10.1016/j.hermed.2022.100611 (IF: 2.5).
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Chauhan P, Bhargava A, Kumari R, Ratre P, Tiwari R, Srivastava RK, Yu Goryacheva I, Kumar Mishra P. Surface-enhanced Raman scattering biosensors for detection of oncomiRs in breast cancer. Drug Discov Today. 2022 Aug;27(8):2121-2136. doi: 10.1016/j.drudis.2022.04.016. Epub 2022 Apr 20. PMID: 35460892.
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Agrawal D, Kumari R, Ratre P, Rehman A, Srivastava RK, Reszka E, Goryacheva I, Mishra PK, *. Cell-free circulating miRNAs-lncRNAs-mRNAs as predictive markers for breast cancer risk assessment in women exposed to indoor air pollution. Case Studies in Chemical and Environmental Engineering (2022), doi : https://doi.org/10.1016/j.cscee.2022.100267 (IF : 4.5).
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Ratre P, Jain B, Kumari R, Thareja S, Tiwari R, Srivastava RK, Goryacheva IY, Mishra PK. Bioanalytical Applications of Graphene Quantum Dots for Circulating Cell-Free Nucleic Acids: A Review. ACS Omega. 2022 Oct 26;7(44):39586-39602. doi: 10.1021/acsomega.2c05414. PMID: 36385871; PMCID: PMC9648045.
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Tiwari A, Singh G, Choudhir G, Motiwale M, Joshi N, Sharma V, Srivastava RK, Sharma S, Tutone M, Singour PK. Deciphering the Potential of Pre and Pro-Vitamin D of Mushrooms against Mpro and PLpro Proteases of COVID-19: An In Silico Approach. Molecules. 2022 Aug 31;27(17):5620. doi: 10.3390/molecules27175620. PMID: 36080385; PMCID: PMC9458008.
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Ratre P, Chauhan P, Bhargava A, Tiwari R, Thareja S, Srivastava RK, Mishra PK. Nano-engineered vitamins as a potential epigenetic modifier against environmental air pollutants. Rev Environ Health. 2022 Jun 21;38(3):547-564. doi: 10.1515/reveh-2022-0027. PMID: 35724323.
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Sapra L and Srivastava RK*. Bifidobacterium Longum Alleviates Bone Loss and Maintains Bone Health By Modulating The Bregs-Tregs-Th17 Cell Axis In Ovx Mice. Aging Clin Exp Res (2022) 34 (Suppl 1):S35–S474 (IF: 4.5).​
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Akhtar N, Srivastava RK, Shrivastava D. How Losing Sleep Following Vaccination May Weaken the Response to SARS-CoV Vaccines. Sleep Vigil. 2022;6(1):249-251. doi: 10.1007/s41782-022-00195-3. Epub 2022 Feb 17. PMID: 35194570; PMCID: PMC8853391.
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Sapra L, Bhardwaj A and Srivastava RK*. Gut metabolite 5’-hydroxyindoleacetic acid (HIAA) inhibits osteoclastogenesis. Osteoporos Int. (2022), 33 (Suppl 1):S41 https://doi.org/10.1007/s00198-022-06343-9 (IF: 5.0).
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Bhardwaj A, Sapra L and Srivastava RK*. Bifidobacterium longum inhibits bone loss in Osteoporotic mice via inducing ptregs in gut. Osteoporos Int. (2022), 33 (Suppl 1):S38 https://doi.org/10.1007/s00198-022-06343-9 (IF: 5.0).
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Sapra L, Bhardwaj A and Srivastava RK*. Bifidobacterium longum attenuates bone loss and maintains bone health by modulating bregs-tregs-th17 cell axis in ovx mice. Osteoporos Int. (2022), 32 (Suppl 1):S226 https://doi.org/ 10.1007/s00198-021-06125-9 (IF:5.0).
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Bhardwaj A, Sapra L and Srivastava RK*. Lactobacillus rhamnosus enhances bone health via modulating peripheral tregs (ptregs) in osteoporotic mice. Osteoporos Int. (2022), 32 (Suppl 1):S256 (IF: 5.0).
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Srivastava RK* and Sapra L. IL- 10 producing Bregs suppress osteoclastogenesis and regulate inflammatory bone loss in osteoporosis. Journal of Bone and Mineral Research (2022), 37(Suppl 1), P177. https://doi.org/10.1002/jbmr.4515, (IF : 6.832).
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Bhardwaj A, Sapra L, Verma B and Srivastava RK*. Homocysteine and Bone Health. Springer Nature (2022). https://doi.org/10.1007/978-981-16-6867-8_4.
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Tiwari A, Singh G, Chowdhary K, Choudhir G, Sharma V, Sharma S and Srivastava RK. Co-Product Recovery in Food Processing. Springer Nature (2022). https://doi.org/10.1007/978-981-19-1746-2_12.
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2021​
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Sapra L, Bhardwaj A, Mishra PK, Garg B, Verma B, Mishra GC, Srivastava RK. Regulatory B Cells (Bregs) Inhibit Osteoclastogenesis and Play a Potential Role in Ameliorating Ovariectomy-Induced Bone Loss. Front Immunol. 2021 Jun 30;12:691081. doi: 10.3389/fimmu.2021.691081. PMID: 34276682; PMCID: PMC8278221.
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Sapra L, Dar HY, Bhardwaj A, Pandey A, Kumari S, Azam Z, Upmanyu V, Anwar A, Shukla P, Mishra PK, Saini C, Verma B, Srivastava RK. Lactobacillus rhamnosus attenuates bone loss and maintains bone health by skewing Treg-Th17 cell balance in Ovx mice. Sci Rep. 2021 Jan 19;11(1):1807. doi: 10.1038/s41598-020-80536-2. PMID: 33469043; PMCID: PMC7815799.
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Tiwari A, Singh G, Sharma V, Srivastava RK, Sharma S. Harnessing the potential of UVB irradiation for improving the nutraceutical properties of edible xylotrophic mushroom dried powder. LWT - Food Science and Technology (2021). https://doi.org/10.1016/j.lwt.2021.111913. (IF : 6.0).
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Ranjan S, Jain S, Bhargava A, Shandilya R, Srivastava RK, Mishra PK. Lateral flow assay-based detection of long non-coding RNAs: A point-of-care platform for cancer diagnosis. J Pharm Biomed Anal. 2021 Sep 10;204:114285. doi: 10.1016/j.jpba.2021.114285. Epub 2021 Jul 27. PMID: 34333453.
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Bhardwaj A, Sapra L, Saini C, Azam Z, Mishra PK, Verma B, Mishra GC, Srivastava RK. COVID-19: Immunology, Immunopathogenesis and Potential Therapies. Int Rev Immunol. 2022;41(2):171-206. doi: 10.1080/08830185.2021.1883600. Epub 2021 Feb 27. PMID: 33641587; PMCID: PMC7919479.
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Saini R, Azam Z, Sapra L, Srivastava RK. Neuronal Nitric Oxide Synthase (nNOS) in Neutrophils: An Insight. Rev Physiol Biochem Pharmacol. 2021;180:49-83. doi: 10.1007/112_2021_61. PMID: 34115206.
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Sapra L, Bhardwaj A, Azam Z, Madhry D, Verma B, Rathore S, Srivastava RK. Phytotherapy for treatment of cytokine storm in COVID-19. Front Biosci (Landmark Ed). 2021 Apr 30;26(5):51-75. doi: 10.52586/4924. PMID: 34027650.
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Sapra L, Azam Z, Rani L, Saini C, Bhardwaj A, Shokeen N, Ahmad A, Mishra GC and Srivastava RK*. “Immunoporosis”: Immunology of Osteoporosis. Proc. Natl. Acad. Sci., India, Sect. B Biol. Sci. (2021) 10.1007/s40011-021-01238-x (Invited Review).
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Srivastava RK, Schmidt-Bleek K, Chattopadhyay N, De Martinis M, Mishra PK. Editorial: Recent Advances in Basic and Translational Osteoimmunology. Front Immunol. 2021 Nov 18;12:800508. doi: 10.3389/fimmu.2021.800508. PMID: 34868088; PMCID: PMC8636454.
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Tiwari A, Singh G, Singh U, Sapra L, Rana V, Sharma V, Srivastava RK & Sharma S*. Edible mushrooms: The potential game changer in alleviating vitamin D deficiency and improving human health. International Journal of Food Science and Technology (2021). doi:10.1111/ijfs.15410. (IF : 3.7).
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Pandey KK, Madhry D, Kumar YS, Malvankar S, Sapra L, Srivastava RK, Bhattacharyya S, Verma B. Regulatory roles of tRNA-derived RNA fragments in human pathophysiology. Mol Ther Nucleic Acids. 2021 Jul 2;26:161-173. doi: 10.1016/j.omtn.2021.06.023. PMID: 34513302; PMCID: PMC8413677.
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Madhry D, Pandey KK, Kaur J, Rawat Y, Sapra L, Srivastava RK, Bhattacharyya S, Verma B. Role of non-coding RNAs in Dengue virus-host interaction. Front Biosci (Schol Ed). 2021 Jun 30;13(1):44-55. doi: 10.52586/S552. PMID: 34256529.
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Sapra L, Bhardwaj A, Mishra PK, Garg B, Verma B, Mishra GC, Srivastava RK. Regulatory B Cells (Bregs) Inhibit Osteoclastogenesis and Play a Potential Role in Ameliorating Ovariectomy-Induced Bone Loss. Front Immunol. 2021 Jun 30;12:691081. doi: 10.3389/fimmu.2021.691081. PMID: 34276682; PMCID: PMC8278221.
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Singh A, Malvankar S, Pandey KK, Kumar S, Srivastava RK and Verma B. Transcriptomics Approaches to Study Role of ncRNAs in Reproductive Health. Indian Society for Study of Reproduction and Fertility (ISSRF) 27th Newsletter. (2021, Feb., 20) (ISSN # 2395-2806).
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Editor-eBook: Srivastava, R. K.*, Chattopadhyay, N., Schmidt-Bleek, K., Mishra, P. K., De Martinis, M., eds. (2021). Recent Advances in Basic and Translational Osteoimmunology. Lausanne: Frontiers Media SA. doi: 10.3389/978-2-88974-014-7.
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Srivastava RK, Schmidt-Bleek K, Chattopadhyay N, De Martinis M, Mishra PK. Editorial: Recent Advances in Basic and Translational Osteoimmunology. Front Immunol. 2021 Nov 18;12:800508. doi: 10.3389/fimmu.2021.800508. PMID: 34868088; PMCID: PMC8636454.
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Srivastava RK*. Immune system and COVID-19 Management and potential therapies (2021). Issue 41. Pharma Focus Asia.
2020​
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Bunkar N, Sharma J, Chouksey A, Kumari R, Gupta PK, Tiwari R, Lodhi L, Srivastava RK, Bhargava A, Mishra PK. Clostridium perfringens phospholipase C impairs innate immune response by inducing integrated stress response and mitochondrial-induced epigenetic modifications. Cell Signal. 2020 Nov;75:109776. doi: 10.1016/j.cellsig.2020.109776. Epub 2020 Sep 8. PMID: 32916276.
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Saini C, Srivastava RK, Tarique M, Kurra S, Khanna N, Ramesh V, Sharma A. Elevated IL-6R on CD4+ T cells promotes IL-6 driven Th17 cell responses in patients with T1R leprosy reactions. Sci Rep. 2020 Sep 15;10(1):15143. doi: 10.1038/s41598-020-72148-7. PMID: 32934336; PMCID: PMC7493991.
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Saini C, Srivastava RK, Kumar P, Ramesh V, Sharma A. A distinct double positive IL-17A+/F+ T helper 17 cells induced inflammation leads to IL17 producing neutrophils in Type 1 reaction of leprosy patients. Cytokine. 2020 Feb;126:154873. doi: 10.1016/j.cyto.2019.154873. Epub 2019 Oct 16. PMID: 31629113.
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Azam Z, Pandey V, Gupta N, Sapra L, Dar HY, Shokeen N, Soni V, Srivastava RK. Phytoconstituents as novel osteo-protective agents: Implications in bone health. Front Biosci (Landmark Ed). 2020 Mar 1;25(7):1259-1296. doi: 10.2741/4855. PMID: 32114432.
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Srivastava RK*, Sapra L, Bhardwaj A, Ahmad A, Azam Z. Sodium Benzoate (NaB) attenuates osteoporosis and enhances bone health via modulating host osteoimmune system. Journal of Bone and Mineral Research (2020), 35(Suppl 1),P91.doi.org/10.1002/jbmr.4206, (IF : 6.832).
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Sapra L, Tejaswini M, Azam Z, Bhardwaj A, Srivastava RK*. Cyanotoxin “MC-LR” induces Bone Loss by modulating Treg-Th17 Immune Cell Axis Osteoporos Int. (2020), 31 (Suppl 1):S516. https://doi.org/10.1007/s00198-020-05696-3 (IF: 5.0).
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Bhardwaj A, Dar HY, Pandey A, Sapra L, Azam Z, Srivastava RK.* Lactobacillus rhamnosus Enhances Bone Health In Osteoporotic Mice via Modulating Host Immune System. Osteoporos Int. (2020), 31 (Suppl 1):S515. https://doi.org/10.1007/s00198-020-05696-3 (IF: 5.0).
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Azam Z, Dar HY, Sapra L, Bhardwaj A, Srivastava RK*. Noncaloric Artificial Sweetener-Aspartame (NAS-A) intake and Bone Health: Role of Th17-Treg Cell Axis. Osteoporos Int. (2020), 31 (Suppl 1):S522. https://doi.org/10.1007/s00198-020-05696-3 (IF:5.0).
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Saini C, Srivastava RK, Khanna N, Ramesh V, Sharma A. IL-6 promotes pathogenic Th17 in T1R leprosy reactions bystimulating Il17 producing by IL-6R pathway. International Journal of Infectious Diseases (2020) P462-463:101(6). doi.org/10.1016/j.ijid.2020.09.1212. (IF: 12.03).
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Sapra L, Bhardwaj A, Azam Z, Anwar A, Upmanyu V and Srivastava RK*. Nano encapsulation of curcumin to enhance its anti-osteoporotic efficacy in post-menopausal osteoporosis. Indian Society for Study of of Reproduction and Fertility (ISSRF) 26th Newsletter. (2020, Sep., 52-56) (ISSN # 2395-2806).
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2019​
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Namdev P, Lyngdoh DL, Dar HY, Chaurasiya SK, Srivastava RK, Tripathi T, Anupam R. Intrinsically Disordered Human T Lymphotropic Virus Type 1 p30 Protein: Experimental and Computational Evidence. AIDS Res Hum Retroviruses. 2019 May;35(5):477-487. doi: 10.1089/AID.2018.0196. Epub 2019 Feb 6. PMID: 30618266.
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Bhatwalkar SB, Shukla P, Srivastava RK, Mondal R, Anupam R. Validation of environmental disinfection efficiency of traditional Ayurvedic fumigation practices. J Ayurveda Integr Med. 2019 Jul-Sep;10(3):203-206. doi: 10.1016/j.jaim.2019.05.002. Epub 2019 Aug 16. PMID: 31427141; PMCID: PMC6822153.
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Bhatwalkar SB, Gound SS, Mondal R, Srivastava RK, Anupam R. Anti-biofilm and Antibacterial Activity of Allium sativum Against Drug Resistant Shiga-Toxin Producing Escherichia coli (STEC) Isolates from Patient Samples and Food Sources. Indian J Microbiol. 2019 Jun;59(2):171-179. doi: 10.1007/s12088-019-00784-3. Epub 2019 Feb 18. PMID: 31031431; PMCID: PMC6458215.
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Namdev P, Dar HY, Srivastava RK, Mondal R, Anupam R. Induction of T7 Promoter at Higher Temperatures May Be Counterproductive. Indian J Clin Biochem. 2019 Jul;34(3):357-360. doi: 10.1007/s12291-019-0813-y. Epub 2019 Feb 8. PMID: 31391729; PMCID: PMC6660524.
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Bunkar N, Shandilya R, Bhargava A, Samarth RM, Tiwari R, Mishra DK, Srivastava RK, Sharma RS, Lohiya NK, Mishra PK. Nano-engineered flavonoids for cancer protection. Front Biosci (Landmark Ed). 2019 Mar 1;24(6):1097-1157. doi: 10.2741/4771. PMID: 30844733.
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Srivastava RK* and H. Y. Dar. Sodium Benzoate (Nab) - A Food Additive, Inhibits bone loss by upregulating anti-Osteoclastogenic T Cells. Osteoporos Int. (May, 2019), P110: 30(1). https://doi.org/10.1007/s00198-018-04815-5 (IF: 5.0).
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Hamid Y. Dar & Srivastava RK. Lactobacillus rhamnosus (LR) enhances Bone Health In Osteoporotic Mice Model (Ovx) By Regulating Treg-Th17 Balance. Osteoporos Int. (May, 2019), P064: 30(1). https://doi.org/10.1007/s00198-018-04815-5 (IF: 5.0).
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Invited Editor of 24th Newsletter of Indian Society for the study of Reproduction & Fertility (ISSRF), India, 2019 with thematic focus on “Translational Research in Reproductive Health” (ISSN 2395-2806).
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Sapra L, Shokeen N, Azam Z, Bhardwaj A, Ahmad A and Srivastava RK*. Testicular Macrophages: Caretakers of Testicular Niche (invited review). Indian Society for Study of Reproduction and Fertility (ISSRF) 24th Newsletter (2019, Sep., 24, 21- 22), (ISSN # 2395-2806).
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Dar HY, Sapra L, Kumari S, Srivastava RK*. How salt hate your bones: the nexus between high dietary salt intake and bone loss. Atlas of Science, (March 21, 2019).(https://atlasofscience.org/how-salt-hate-your-bones-the-nexus-between-high-dietary-salt-intake-and-bone-loss/
2018
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Dar HY, Singh A, Shukla P, Anupam R, Mondal RK, Mishra PK, Srivastava RK. High dietary salt intake correlates with modulated Th17-Treg cell balance resulting in enhanced bone loss and impaired bone-microarchitecture in male mice. Sci Rep. 2018 Feb 6;8(1):2503. doi: 10.1038/s41598-018-20896-y. PMID: 29410520; PMCID: PMC5802842.
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Dar HY, Pal S, Shukla P, Mishra PK, Tomar GB, Chattopadhyay N, Srivastava RK. Bacillus clausii inhibits bone loss by skewing Treg-Th17 cell equilibrium in postmenopausal osteoporotic mice model. Nutrition. 2018 Oct;54:118-128. doi: 10.1016/j.nut.2018.02.013. Epub 2018 Mar 20. PMID: 29793054.
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Dar HY, Lone Y, Koiri RK, Mishra PK, Srivastava RK. Microcystin-leucine arginine (MC-LR) induces bone loss and impairs bone micro-architecture by modulating host immunity in mice: Implications for bone health. Environ Pollut. 2018 Jul;238:792-802. doi: 10.1016/j.envpol.2018.03.059. Epub 2018 Apr 4. PMID: 29626823.
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Dar HY, Shukla P, Mishra PK, Anupam R, Mondal RK, Tomar GB, Sharma V, Srivastava RK. Lactobacillus acidophilus inhibits bone loss and increases bone heterogeneity in osteoporotic mice via modulating Treg-Th17 cell balance. Bone Rep. 2018 Feb 5;8:46-56. doi: 10.1016/j.bonr.2018.02.001. Erratum in: Bone Rep. 2021 Apr 30;14:101086. doi: 10.1016/j.bonr.2021.101086. PMID: 29955622; PMCID: PMC6019967.
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Dar HY, Azam Z, Anupam R, Mondal RK, Srivastava RK. Osteoimmunology: The Nexus between bone and immune system. Front Biosci (Landmark Ed). 2018 Jan 1;23(3):464-492. doi: 10.2741/4600. PMID: 28930556.
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Singh RD, Shandilya R, Bhargava A, Kumar R, Tiwari R, Chaudhury K, Srivastava RK, Goryacheva IY, Mishra PK. Quantum Dot Based Nano-Biosensors for Detection of Circulating Cell Free miRNAs in Lung Carcinogenesis: From Biology to Clinical Translation. Front Genet. 2018 Dec 6;9:616. doi: 10.3389/fgene.2018.00616. PMID: 30574163; PMCID: PMC6291444.
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Bhargava A, Srivastava RK, Mishra DK, Tiwari RR, Sharma RS & Mishra PK. Dendritic cell engineering for selective targeting of female reproductive tract cancers. Indian J Med Res (2018) 148 (Supplement), December 2018, pp 50-63. DOI: 10.4103/ijmr.IJMR_224_18. (IF : 2.5)
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Srivastava RK, Dar HY, Mishra PK. Immunoporosis: Immunology of Osteoporosis-Role of T Cells. Front Immunol. 2018 Apr 5;9:657. doi: 10.3389/fimmu.2018.00657. PMID: 29675022; PMCID: PMC5895643.
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Dar HY & Srivastava RK*. Bacillus clausii (BC) inhibits ovariectomy induced osteoporosis via modulation of Treg Th17 cells. Osteoporos Int. (2018), P1019: 29(1), (IF:5.0).
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Srivastava RK. Immunoporosis: The Immunology of Osteoporosis. Molecular Medicine- Bench to Bedside and Beyond,1st Ed. pp 288-304, 2018, (ISBN 978-81-936756-0-1). Indian Society for the study of Reproduction and Fertility (ISSRF).
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Srivastava RK*. Algal-Bloom-Produced Toxins Negatively Affect Our Osteo-Immune System. Science Trends (2018). DOI: 10.31988/SciTrends.20358.
2017​
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Bhargava A, Tamrakar S, Aglawe A, Lad H, Srivastava RK, Mishra DK, Tiwari R, Chaudhury K, Goryacheva IY, Mishra PK. Ultrafine particulate matter impairs mitochondrial redox homeostasis and activates phosphatidylinositol 3-kinase mediated DNA damage responses in lymphocytes. Environ Pollut. 2018 Mar;234:406-419. doi: 10.1016/j.envpol.2017.11.093. Epub 2017 Dec 1. PMID: 29202419.
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Dar HY and Srivastava RK*. Lactobacillus acidophilus enhances trabecular and cortical bone microarchitecture in ovx mice via modulating host immune system. Osteoporosis and Sarcopenia, 3 (2017) S1eS17. (ISSN # 2405-5255) (DOI: 10.1016/j.afos.2017.08.009).
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Srivastava RK * and Dar HY. Hi dietary salt intake induces bone loss in ovx mice by skewing Treg-Th17 balance. Osteoporosis and Sarcopenia 3 (2017) S1eS17. (ISSN # 2405- 5255) (DOI: 10.1016/j.afos.2017.08.077).
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Dar HY, Choudhary ZA, Srivastava RK *. Hi-Salt Diet Induces Bone Loss. Osteoporosis International (2017) 28 (Suppl 1), DOI 10.1007/s00198-017-3950-2, ISSN 0937-941X (Print) 1433-2965 (Online). (IF : 5.0).
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Dar HY, Chaturvedi S, Srivastava K, Azam Z, Anupam R, Mondal R, Tomar GB, Singh AK, Mishra PK and Srivastava RK*. Immunomodulatory Effects of Food Additives. Int J Immunother Cncer Res (2017) 3(1):019-031.
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Priyanka N, Rajesh MK, Rupesh SK, Soni V, Anupam R. An Account of Dengue Epidemics in Central India. J Clin Microbiol Biochem Technol (2017) 3(2):031-034.
2016​
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Bhargava A, Mishra DK, Jain SK, Srivastava RK, Lohiya NK, Mishra PK. Comparative assessment of lipid-based nano-carrier systems for dendritic cell-based targeting of tumor re-initiating cells in gynecological cancers. Mol Immunol. 2016 Nov;79:98-112. doi: 10.1016/j.molimm.2016.10.003. Epub 2016 Oct 17. PMID: 27764711.
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Chaudhuri L, Srivastava RK, Kos F, Shrikant PA. Uncoupling protein 2 regulates metabolic reprogramming and fate of antigen-stimulated CD8+ T cells. Cancer Immunol Immunother. 2016 Jul;65(7):869-74. doi: 10.1007/s00262-016-1851-4. Epub 2016 Jun 6. PMID: 27271549; PMCID: PMC4919150.
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Srivastava RK*, Dar HY. Lactobacillus acidophilus inhibits bone loss in osteoporotic mice by modulating Th17-Treg cell balance. Osteoporosis International (2016) 27 (Suppl 3):S709–S787. DOI 10.1007/s00198-016-3747-8. ISSN 1433-2965 (Online). (IF : 5.0).
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R. Brightwell , A. Amobi , K. Wooten , R. Srivastava , K.O. Odunsi , P. Shrikant. Developing combinatorial approaches for durable cancer treatment. Gynecologic Oncology 141 (2016) 197. ISSN: 0090-8258, doi:10.1016/j.ygyno.2016.04.509, (IF : 5.3).
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Srivastava RK*, Dar HY and Singh A. The Kinship netween Salt and Fertility (invited review). Indian Society for Study of Reproduction and Fertility (ISSRF) Newsletter (2016, Sep., 19, 51-53), (ISSN # 2395-2806).
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Srivastava RK*. Is High Salt Intake Making Us Infertile - Are Th17 Cells To Blame? (invited review). Indian Society for Study of Reproduction and Fertility (ISSRF) Newsletter (2016, Feb. 18, 28-31), (ISSN # 2395-2806).
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2009-2015
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Yousf H, Tomar GB, Srivastava RK*. Probiotics and Bone Health: It takes GUTS to Improve Bone Density (Corresponding Auth.). Int J Immunother Cancer Res (2015) 1(1): 018-022. ISSN : 2455-8591.
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Srivastava RK*. Pre-eclampsia and Recurrent Pregnancy Loss: Emerging Role of Th17 Cells (invited review). Indian Society for Study of Reproduction and Fertility (ISSRF) Newsletter (2015, Feb. 15, 57-60), (ISSN # 2395-2806).
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Srivastava RK, Utley A, Shrikant PA. Rapamycin: A rheostat for CD8(+) T-cell-mediated tumor therapy. Oncoimmunology. 2012 Oct 1;1(7):1189-1190. doi: 10.4161/onci.20663. PMID: 23170275; PMCID: PMC3494641.
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Barhanpurkar AP, Gupta N, Srivastava RK, Tomar GB, Naik SP, Joshi SR, Pote ST, Mishra GC, Wani MR. IL-3 promotes osteoblast differentiation and bone formation in human mesenchymal stem cells. Biochem Biophys Res Commun. 2012 Feb 24;418(4):669-75. doi: 10.1016/j.bbrc.2012.01.074. Epub 2012 Jan 24. PMID: 22293197.
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Srivastava RK, Tomar GB, Barhanpurkar AP, Gupta N, Pote ST, Mishra GC, Wani MR. IL-3 attenuates collagen-induced arthritis by modulating the development of Foxp3+ regulatory T cells. J Immunol. 2011 Feb 15;186(4):2262-72. doi: 10.4049/jimmunol.1002691. Epub 2011 Jan 17. PMID: 21242512.
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Srivastava RK, Tomar GB, Barhanpurkar AP, Gupta N, Pote ST, Mishra GC, Wani MR. IL-3 attenuates collagen-induced arthritis by modulating the development of Foxp3+ regulatory T cells. J Immunol. 2011 Feb 15;186(4):2262-72. doi: 10.4049/jimmunol.1002691. Epub 2011 Jan 17. PMID: 21242512.
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Barhanpurkar AP, Gupta N, Srivastava RK, Tomar GB, Naik SP, Joshi SR, Pote ST, Mishra GC, Wani MR. IL-3 promotes osteoblast differentiation and bone formation in human mesenchymal stem cells. Biochem Biophys Res Commun. 2012 Feb 24;418(4):669-75. doi: 10.1016/j.bbrc.2012.01.074. Epub 2012 Jan 24. PMID: 22293197.
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Gupta N, Barhanpurkar AP, Tomar GB, Srivastava RK, Kour S, Pote ST, Mishra GC, Wani MR. IL-3 inhibits human osteoclastogenesis and bone resorption through downregulation of c-Fms and diverts the cells to dendritic cell lineage. J Immunol. 2010 Aug 15;185(4):2261-72. doi: 10.4049/jimmunol.1000015. Epub 2010 Jul 19. PMID: 20644169.
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Gupta N, Barhanpurkar AP, Tomar GB, Srivastava RK, Kour S, Pote ST, Mishra GC, Wani MR. IL-3 inhibits human osteoclastogenesis and bone resorption through downregulation of c-Fms and diverts the cells to dendritic cell lineage. J Immunol. 2010 Aug 15;185(4):2261-72. doi: 10.4049/jimmunol.1000015. Epub 2010 Jul 19. PMID: 20644169.
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Tomar GB, Srivastava RK, Gupta N, Barhanpurkar AP, Pote ST, Jhaveri HM, Mishra GC, Wani MR. Human gingiva-derived mesenchymal stem cells are superior to bone marrow-derived mesenchymal stem cells for cell therapy in regenerative medicine. Biochem Biophys Res Commun. 2010 Mar 12;393(3):377-83. doi: 10.1016/j.bbrc.2010.01.126. Epub 2010 Feb 6. PMID: 20138833.
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Yogesha SD, Khapli SM, Srivastava RK, Mangashetti LS, Pote ST, Mishra GC, Wani MR. IL-3 inhibits TNF-alpha-induced bone resorption and prevents inflammatory arthritis. J Immunol. 2009 Jan 1;182(1):361-70. doi: 10.4049/jimmunol.182.1.361. PMID: 19109167.